Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes.

  title={Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes.},
  author={Stephan Baldus and Christopher Heeschen and Thomas Meinertz and Andreas Michael Zeiher and Jason P. Eiserich and Thomas F. M{\"u}nzel and Maarten L. Simoons and C. W. Hamm},
  volume={108 12},
BACKGROUND Polymorphonuclear neutrophils (PMNs) have gained attention as critical mediators of acute coronary syndromes (ACS). Myeloperoxidase (MPO), a hemoprotein abundantly expressed by PMNs and secreted during activation, possesses potent proinflammatory properties and may contribute directly to tissue injury. However, whether MPO also provides prognostic information in patients with ACS remains unknown. METHODS AND RESULTS MPO serum levels were assessed in 1090 patients with ACS. We… CONTINUE READING
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