Myeloma kidney: toward its prevention--with new insights from in vitro and in vivo models of renal injury.

Abstract

Renal involvement in patients with multiple myeloma complicates their treatment and shortens their life span. The main renal lesion is predominantly a tubulointerstitial disease characterized by fibrosis, frequently associated with light chain-containing casts. At present there is no effective treatment for kidney disease associated with multiple myeloma… (More)

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