Myeloma immunoglobulin interferes with serum thyroxine analysis by homogeneous enzyme immunoassay.

Abstract

Myeloma immunoglobulin paraproteins interfere with a homogeneous enzyme immunoassay (EMIT) for serum thyroxine. The EMIT assay failed to detect any hormone in three hyperproteinemic sera from multiple myeloma patients, although thyroxine in these sera was accurately measured by our competitive protein-binding radio-assay on small, re-usable Sephadex columns… (More)

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@article{Alexander1980MyelomaII, title={Myeloma immunoglobulin interferes with serum thyroxine analysis by homogeneous enzyme immunoassay.}, author={Nicholas M. Alexander and R Gattra and Marc Nishimoto}, journal={Clinica chimica acta; international journal of clinical chemistry}, year={1980}, volume={100 3}, pages={301-5} }