Myeloid progenitor cells transformed by the myeloproliferative leukemia virus proliferate and differentiate in vitro without the addition of growth factors.

@article{Wendling1989MyeloidPC,
  title={Myeloid progenitor cells transformed by the myeloproliferative leukemia virus proliferate and differentiate in vitro without the addition of growth factors.},
  author={Françoise Wendling and Isabelle Vigon and Mich{\`e}le Souyri and Pierre E. Tambourin},
  journal={Leukemia},
  year={1989},
  volume={3 7},
  pages={475-80}
}
The myeloproliferative leukemia virus (MPLV) is an acute leukemogenic, nonsarcomatogenic replication-defective murine retrovirus which carries a novel oncogene, termed mpl. We recently reported that both late and early erythroid progenitors from MPLV-infected mice acquire erythropoietin and growth factor independence. In the present study, we show that MPLV… CONTINUE READING