Myeloid differentiation factor 88 gene is involved in antiviral immunity in grass carp Ctenopharyngodon idella.

@article{Su2011MyeloidDF,
  title={Myeloid differentiation factor 88 gene is involved in antiviral immunity in grass carp Ctenopharyngodon idella.},
  author={Jianguo Su and Juan Dong and Tianren Huang and Rongfang Zhang and Chunxia Yang and J. Heng},
  journal={Journal of fish biology},
  year={2011},
  volume={78 3},
  pages={973-9}
}
A full-length MyD88 cDNA (CiMyD88) was cloned and characterized from grass carp Ctenopharyngodon idella. CiMyD88 was found to be broadly expressed and was up-regulated by grass carp reovirus (GCRV) and CiMyD88 transcripts in vitro were rapidly elevated in C. idella kidney (CIK) cells after challenge with poly(I:C). These results suggest that CiMyD88 may be involved in the antiviral immune defence in C. idella.