Myeloid-derived suppressor cells in glioma.

  title={Myeloid-derived suppressor cells in glioma.},
  author={Masoud Mirghorbani and Stefaan Van Gool and Nima Attaran Rezaei},
  journal={Expert review of neurotherapeutics},
  volume={13 12},
Glioblastoma is the most prevalent form of gliomas with high aggressive nature and high recurrence. Despite aggressive therapy, including surgery, chemotherapy and radiotherapy, median patient survival is only about 15 months. Hence, developing novel and efficient therapies seem urgent. Many fields have begun their work in preclinical studies but gained limited success in clinical phases. One of the most notable reasons is tumor-induced immunosuppression. In recent decade, efforts to dissect… CONTINUE READING