Myeloid-derived suppressor cells are essential for maintaining feto-maternal immunotolerance via STAT3 signaling in mice.

Abstract

Maternal immune system tolerance to the semiallogeneic fetus is essential for a successful pregnancy; however, the mechanisms underlying this immunotolerance have not been fully elucidated. Here, we demonstrate that myeloid-derived suppressor cells play an important role in maintaining feto-maternal tolerance. A significant expansion of granulocytic myeloid… (More)
DOI: 10.1189/jlb.1A1015-481RR

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@article{Pan2016MyeloidderivedSC, title={Myeloid-derived suppressor cells are essential for maintaining feto-maternal immunotolerance via STAT3 signaling in mice.}, author={Ting Pan and Yufeng Liu and Li Zhong and Mao Shi and Xiao Bing Duan and Kang Wu and Qiong Yang and Chao Liu and Jian Wei and Xing Ma and Kun Shi and Hui Zhang and Jie Zhou}, journal={Journal of leukocyte biology}, year={2016}, volume={100 3}, pages={499-511} }