Myeloid cell leukemia-1 (Mc1-1) is a candidate target gene of hypoxia-inducible factor-1 (HIF-1) in the testis

@inproceedings{Palladino2012MyeloidCL,
  title={Myeloid cell leukemia-1 (Mc1-1) is a candidate target gene of hypoxia-inducible factor-1 (HIF-1) in the testis},
  author={Michael A Palladino and Anoop Dinesh Shah and Rebecca Tyson and Jaclyn Horvath and Christine Dugan and Marie Karpodinis},
  booktitle={Reproductive biology and endocrinology : RB&E},
  year={2012}
}
BACKGROUND Spermatic cord torsion can lead to testis ischemia (I) and subsequent ischemia-reperfusion (I/R) causing germ cell-specific apoptosis. Previously, we demonstrated that the hypoxia-inducible factor-1 (HIF-1) transcription factor, a key regulator of physiological responses to hypoxia, is abundant in Leydig cells in normoxic and ischemic testes. We… CONTINUE READING