Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.

@article{Duployez2016MyelodysplasticSA,
  title={Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.},
  author={Nicolas Duployez and Sophie Lejeune and Aline Renneville and Claude Joseph Preudhomme},
  journal={Expert review of hematology},
  year={2016},
  volume={9 12},
  pages={1189-1202}
}
INTRODUCTION The determination of an underlying genetic predisposition is not automatically part of the diagnosis of hematological malignancies (HM) in routine practice. However, it is assumed that genetic predispositions to HM are currently underestimated due to great variations in disease phenotype, variable latency and incomplete penetrance. Most of patients do not display any biological or clinical signs besides the overt hematological disease and many of them have a lack of personal or… CONTINUE READING
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