Myelodysplastic syndrome with thrombocytosis in a patient with Klinefelter's syndrome.

@article{Yamauchi1993MyelodysplasticSW,
  title={Myelodysplastic syndrome with thrombocytosis in a patient with Klinefelter's syndrome.},
  author={Kunihiko Yamauchi},
  journal={Acta haematologica},
  year={1993},
  volume={89 1},
  pages={43-5}
}
We report herein a patient with Klinefelter's syndrome associated with refractory anemia with excess of blasts in transformation, a subtype of myelodysplastic syndrome (MDS). The MDS developed with karyotypic abnormality involving t(4;7)(q21;q11), and was characteristic of marked thrombocytosis and marrow infiltration by many atypical megakaryocytes. The patient also had diabetes mellitus and a disturbed immune system. To our knowledge, this is the fifth reported case of MDS in patients with… CONTINUE READING

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