Myelodysplastic syndrome is not merely "preleukemia".

  title={Myelodysplastic syndrome is not merely "preleukemia".},
  author={Maher Albitar and Taghi Manshouri and Y J Shen and Diane C Liu and Miloslav E Beran and Hagop M Kantarjian and Anna Rogers and Iman B Jilani and Chung Wu Lin and Sherry M Pierce and Emil J. Freireich and Elihu Estey},
  volume={100 3},
Myelodysplastic syndrome (MDS) is a disease characterized by ineffective hematopoiesis. There are significant biologic and clinical differences between MDS and acute myeloid leukemia (AML). We studied a cohort of 802 patients, 279 (35%) with newly diagnosed MDS and 523 (65%) with newly diagnosed AML, and compared clinical and biologic characteristics of the 2 groups. Complete clinical and cytogenetic data were available on all patients, and a subgroup of patients was studied for apoptosis… CONTINUE READING


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