Myeloablative radiochemotherapy followed by autologous stem cell transplantation in first remission prolongs progression-free survival in follicular lymphoma: results of a prospective, randomized trial of the German Low-Grade Lymphoma Study Group.

@article{Lenz2004MyeloablativeRF,
  title={Myeloablative radiochemotherapy followed by autologous stem cell transplantation in first remission prolongs progression-free survival in follicular lymphoma: results of a prospective, randomized trial of the German Low-Grade Lymphoma Study Group.},
  author={G. Lenz and Martin H. Dreyling and Eva Schiegnitz and Roswitha Forstpointner and Hannes Wandt and M. Freund and Georg Hess and Lorenz H. Tr{\"u}mper and Volker Diehl and Martin Kropff and Michael Kneba and Norbert Schmitz and Bernd Metzner and Markus Pfirrmann and Michael Unterhalt and Wolfgang Hiddemann},
  journal={Blood},
  year={2004},
  volume={104 9},
  pages={2667-74}
}
Conventional chemotherapy has failed to substantially prolong survival for patients with advanced follicular lymphoma. To improve outcomes, the German Low-Grade Lymphoma Study Group (GLSG) initiated a randomized trial to compare the effect of potentially curative myeloablative radiochemotherapy followed by autologous stem cell transplantation (ASCT) with interferon-alpha (IFN-alpha) maintenance therapy in first remission. Three hundred seven patients (younger than 60 years) with follicular… CONTINUE READING
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