Myeloablative chemotherapy with stem cell rescue for the treatment of primary systemic amyloidosis: a status report

@article{Gertz2000MyeloablativeCW,
  title={Myeloablative chemotherapy with stem cell rescue for the treatment of primary systemic amyloidosis: a status report},
  author={M Gertz and M Q Lacy and Angela Dispenzieri},
  journal={Bone Marrow Transplantation},
  year={2000},
  volume={25},
  pages={465-470}
}
Stem cell transplantation has been incorporated in the treatment of primary systemic amyloidosis for 5 years. Results reported to date suggest that the response rates are substantially better than those for patients treated with low-dose traditional melphalan and prednisone chemotherapy. Unexpectedly high mortality rates have, however, been reported with stem cell transplantation, reaching 40% in some series. This unexpectedly high mortality appears to be related to multiorgan failure of… CONTINUE READING