Myelinoclastic Diffuse Sclerosis (Schilder's Disease): Report of a Case and Review of the Literature

@article{Afifi1994MyelinoclasticDS,
  title={Myelinoclastic Diffuse Sclerosis (Schilder's Disease): Report of a Case and Review of the Literature},
  author={Adel K. Afifi and William E. Bell and Arnold H. Menezes and Steven A. Moore},
  journal={Journal of Child Neurology},
  year={1994},
  volume={9},
  pages={398 - 403}
}
The clinical, neuroimaging, and neuropathologic features of Schilder's disease in a 17-year-old girl are presented and compared to 11 well-documented cases reported since 1912. The evolution of knowledge about Schilder's disease and the confusion in nomenclature are reviewed. Signs and symptoms in this case and others reported in the literature are nonspecific and may mimic mass lesions. Neuroimaging studies also may mimic brain tumor or abscess; however, the absence of significant edema, the… 

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