Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia.

@article{Irwin2014MyelinOB,
  title={Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia.},
  author={David J Irwin and Corey T McMillan and Eunran Suh and John Powers and Katya Rascovsky and Elisabeth Mccarty Wood and Jon B. Toledo and Steven E Arnold and Virginia M-Y Lee and Vivianna M Van Deerlin and John Q. Trojanowski and Murray Grossman},
  journal={Neurology},
  year={2014},
  volume={83 6},
  pages={
          502-9
        }
}
OBJECTIVE To determine the prognostic utility of tauopathy-associated single nucleotide polymorphisms (SNPs) in sporadic behavioral-variant frontotemporal dementia (bvFTD). METHODS Eighty-one patients with sporadic bvFTD were genotyped for tauopathy-associated SNPs at rs8070723 (microtubule-associated protein tau [MAPT]) and rs1768208 (myelin-associated oligodendrocyte basic protein [MOBP]). We performed a retrospective case-control study comparing age at onset and disease duration between… CONTINUE READING
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