Myelin gangliosides in vertebrates.

  title={Myelin gangliosides in vertebrates.},
  author={F B Cochran and R K Yu and Robert W. Ledeen},
  journal={Journal of neurochemistry},
  volume={39 3},
A phylogenetic survey of brain myelin ganglioside patterns and concentrations has been carried out on 16 vertebrate species. Gangliosides were isolated from purified myelin and found to vary in concentration from 25 micrograms of sialic acid per 100 mg of myelin for goldfish to a value of 395 for turkey. The latter species had approximately equivalent amounts of GM1 and GM4 as the two major gangliosides. The 11 mammals studied all had GM1 as the major ganglioside, with variable amounts of GM4… CONTINUE READING

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