Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions

@article{Clarner2012MyelinDR,
  title={Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions},
  author={Tim Clarner and Felix Diederichs and Katharina Berger and Bernd Denecke and Lin Gan and Paul Van Der Valk and Cordian Beyer and Sandra Amor and Markus Kipp},
  journal={Glia},
  year={2012},
  volume={60}
}
In multiple sclerosis (MS), gray matter pathology is characterized by less pronounced inflammation when compared with white matter lesions. Although regional differences in the cytoarchitecture may account for these differences, the amount of myelin debris in the cortex during a demyelinating event might also be contributory. To analyze the association between myelin debris levels and inflammatory responses, cortical areas with distinct and sparse myelination were analyzed for micro‐ and… 
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