Myelin basic protein isoforms in myelinating and remyelinating rat brain aggregate cultures.

@article{Kruger1999MyelinBP,
  title={Myelin basic protein isoforms in myelinating and remyelinating rat brain aggregate cultures.},
  author={Genevieve M. Kruger and Lara T Diemel and C. A. Copelman and M. Louise Cuzner},
  journal={Journal of neuroscience research},
  year={1999},
  volume={56 3},
  pages={241-7}
}
Recent evidence suggests that myelin basic protein (MBP) exon-2-containing isoforms play a significant role in the onset of myelination because they are more abundant during early development. The pattern of expression of MBP exon-2-containing isoforms was studied in rat brain aggregate cultures during myelination to draw comparisons with the developing brain and at remyelination after demyelinative treatment. The pattern of MBP isoform expression in the aggregate cultures was found to be… CONTINUE READING

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