Myelin basic protein as a possible marker for oligodendroglioma.

  title={Myelin basic protein as a possible marker for oligodendroglioma.},
  author={J untaro Tanaka and Yasuo Hokama and Hiroshige Nakamura},
  journal={Acta pathologica japonica},
  volume={38 10},
To search for a marker for oligodendroglioma, immunohistochemical analysis of myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP) were performed on tissues from 38 oligodendrogliomas. MBP was detected in 14 such tumors, positive cells being characterized by having rather rich cytoplasm containing a large nucleus and a prominent nucleolus. They seemed to be relatively poorly differentiated cells corresponding to oligodendroglioma grade II in the WHO classification, and appeared… CONTINUE READING