Myelin Recovery in Multiple Sclerosis: The Challenge of Remyelination

  title={Myelin Recovery in Multiple Sclerosis: The Challenge of Remyelination},
  author={Maria Podbielska and Naren Lal Banik and Ewa Kurowska and Edward Leo Hogan},
  booktitle={Brain sciences},
Multiple sclerosis (MS) is the most common demyelinating and an autoimmune disease of the central nervous system characterized by immune-mediated myelin and axonal damage, and chronic axonal loss attributable to the absence of myelin sheaths. T cell subsets (Th1, Th2, Th17, CD8+, NKT, CD4+CD25+ T regulatory cells) and B cells are involved in this disorder, thus new MS therapies seek damage prevention by resetting multiple components of the immune system. The currently approved therapies are… CONTINUE READING
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