• Corpus ID: 85778848

Mycotoxins, drugs and other extrolites produced by species in Penicillium subgenus Penicillium

@article{Frisvad2004MycotoxinsDA,
  title={Mycotoxins, drugs and other extrolites produced by species in Penicillium subgenus Penicillium},
  author={Jens Christian Frisvad and J{\o}rn Smedsgaard and Thomas Ostenfeld Larsen and Robert A Samson},
  journal={Studies in Mycology},
  year={2004},
  volume={49},
  pages={201-241}
}
The 58 species in Penicillium subgenus Penicillium produce a large number of bioactive extrolites (secondary metabolites), including several mycotoxins. An overview of these extrolites is presented with original references to the reports on their production and their chemical constitution. 132 extrolite families are reported from the subgenus with an average of 5 extrolite families per species. This is an underestimate as several pigments, volatiles and uncharacterized extro- lites are not… 

Tables from this paper

A critical review of producers of small lactone mycotoxins: patulin, penicillic acid and moniliformin
TLDR
A very large number of filamentous fungi has been reported to produce the small lactone mycotoxins patulin, penicillic acid and moniliformin, and five species have been regarded as doubtful producers or are now regarded as taxonomic synonyms.
Penicillium Species and Their Associated Mycotoxins.
TLDR
The main aspect of the morphology, ecology and toxigenicity of Penicillium foodborne mycotoxigenic species which belong mainly in subgenus Penicllium sections Brevicompacta, Chrysogena, Fasciculata, Penicillsium, and Roquefortorum are summarized.
New penicillin-producing Penicillium species and an overview of section Chrysogena
TLDR
A multigene analysis is presented, combined with phenotypic characters and extrolite data, demonstrating that sect.
Mycotoxins and other secondary metabolites produced in vitro by Penicillium paneum Frisvad and Penicillium roqueforti Thom isolated from baled grass silage in Ireland.
TLDR
The ability of both molds to produce a diverse range of secondary metabolites in vitro and in silage should be a concern to livestock producers.
Ochratoxin A Producing Species in the Genus Penicillium
TLDR
Only some OTA producing species are known to be a potential source of OTA contamination of cereals and certain common foods and beverages such as bread, beer, coffee, dried fruits, grape juice and wine among others.
Taxonomy, chemodiversity, and chemoconsistency of Aspergillus, Penicillium, and Talaromyces species
TLDR
Despite genome sequencing efforts, it is obvious that epigenetic factors play a large role in evolution and function of chemodiversity, and better methods for characterizing the epigenome are needed.
THE EFFECT OF CARBON SOURCE CONCENTRATION ON TOXIGENESIS AND LIPASE ACTIVITY OF Penicillium aurantiogriseum
TLDR
The aim of this work is to study the influence of carbon source concentration on the secondary metabolites production of P. aurantiogriseum in order to fight against this species and also to improve the production of its lipases.
Secondary Metabolites from Penicillium roqueforti, A Starter for the Production of Gorgonzola Cheese
TLDR
To protect consumers’ health and safety, the presence of mycotoxins needs to be verified in food which is widely consumed, above all for products protected by the protected denomination of origin (DOP) label, such as Gorgonzola cheese.
Ochratoxin A and citrinin producing species of the genus Penicillium from feedstuffs.
Identification of biological secondary metabolites in three Penicillium species, P. goditanum,
Microorganisms are important components of soil. Some soil filamentous fungi such asPenicilium produce many bioactive small molecules, or secondary metabolites, that range frombeneficial bioactive
...
...

References

SHOWING 1-10 OF 555 REFERENCES
Classification of terverticillate penicillia based on profiles of mycotoxins and other secondary metabolites
TLDR
Strains of available terverticillate penicillium species and varieties were analyzed for profiles of known mycotoxins and other secondary metabolites produced on Czapek yeast autolysate agar and yeast extract-sucrose agar by using simple thin-layer chromatography screening techniques.
TERVERTICILLATE PENICILLIA: CHEMOTAXONOMY AND MYCOTOXIN PRODUCTION
TLDR
Several new varieties, chemotypes and combinations are proposed, based on profiles of secondary metabolites, morphology and physiological characters, suggesting a high degree of relatedness in the terverticillate penicillia.
Toxin-producing species of Penicillium and the development of mycotoxins in must and homemade wine.
TLDR
It was shown that isofumigaclavine A can be formed under certain circumstances in must and wine, and a qualitative High Performance Liquid Chromatography (HPLC) method for simultaneous determination of isofums A and B, roquefortine C, and PR toxin was developed.
Verrucofortine, a major metabolite of Penicillium verrucosum var. cyclopium, the fungus that produces the mycotoxin verrucosidin.
Verrucofortine [8], an alkaloid derived from tryptophan and leucine, has been isolated from the fungus Penicillium verrucosum var. cyclopium. The structure and absolute configuration have been
Potential mycotoxin problems in mould-fermented sausage
SummaryA considerable proportion of the sausage consumed in many European countries is produced by a mould-fermentation process that does not involve pure culture technics.422Penicillium cultures
Secondary metabolites resulting from degradation of PR toxin by Penicillium roqueforti
TLDR
It is proposed that PR toxin is degraded into PR-imine and PR-amide in the culture medium of P. roqueforti, and the peak production of PR toxin appeared earlier than those of PR-IMine andPR-amide.
Insecticidal activity of penitrems, including penitrem G, a new member of the family isolated from Penicillium crustosum.
TLDR
Penitrem G (7), a new indole-diterpenoid compound, has been isolated together with the already known mycotoxins penitrems A-D and F from the mycelium of Penicillium crustosum Thom and preliminary structure-activity relationships are proposed.
Biochemical Characterization of Ochratoxin A-Producing Strains of the Genus Penicillium
TLDR
It is found that P. nordicum isolates incorporated phenylalanine into verrucine and lumpidin metabolites, a finding which could explain why those isolates produced relatively lower levels of ochratoxins than did most isolates of P. verrucosum.
Cell cytotoxicity and mycotoxin and secondary metabolite production by common penicillia on cheese agar.
TLDR
Fungal extracts from the rest of the studied penicillia were toxic at levels between these two extremes, and the two P. nalgiovense extracts were the most toxic in the MTT-cell culture test.
...
...