Mycosis fungoides: Review of Epidemiological Observations

@article{MoralesSuarezVarela2000MycosisFR,
  title={Mycosis fungoides: Review of Epidemiological Observations},
  author={Maria M. Morales Suarez-Varela and A. Llopis gonz{\'a}lez and A Marquina Vila and Jonathan Bell},
  journal={Dermatology},
  year={2000},
  volume={201},
  pages={21 - 28}
}
Background: Mycosis fungoides (MF) is a chronic cutaneous T-cell lymphoma characterized by small cells with cerebriform nuclei that usually express a mature peripheral T-helper cell (CD4+) immunophenotype. Its evolution is typically quite slow, with years between the first manifestations and development of advanced stages of disease. Objective: The purpose of the present paper is to contribute to the material about MF already present in the literature. The review articles that have appeared to… 

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No statistically significant differences were found in the disease course between early- and adult-onset MF, and the predominant phenotype was CD3+ CD4+CD7–CD8–.

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A survey of the autopsy material of 45 clinically and histologically typical cases of mycosis fungoides (M.F.) revealed extracutaneous involvement in 32, or 71%. The lymph nodes showed diagnosable

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Among 30 different types of treatment employed during the course of this study, highdose electron beam was superior to all other physical and chemotherapeutic modalities and the concept that occupational factors may be implicated in the etiology of mycosis fungoides provides a new dimension to previous pathogenic hypotheses.

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The function of B‐ and T‐lymphocytes in nineteen patients with classical Alibert's mycosis fungoides (MF) was studied. In general there was no evidence of immune depression, not even in those with
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