Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis.

@article{Dooley2011MycophenolateVA,
  title={Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis.},
  author={M. Dooley and D. Jayne and E. Ginzler and D. Isenberg and N. Olsen and D. Wofsy and F. Eitner and G. Appel and G. Contreras and L. Lisk and N. Solomons},
  journal={The New England journal of medicine},
  year={2011},
  volume={365 20},
  pages={
          1886-95
        }
}
BACKGROUND Maintenance therapy, often with azathioprine or mycophenolate mofetil, is required to consolidate remission and prevent relapse after the initial control of lupus nephritis. METHODS We carried out a 36-month, randomized, double-blind, double-dummy, phase 3 study comparing oral mycophenolate mofetil (2 g per day) and oral azathioprine (2 mg per kilogram of body weight per day), plus placebo in each group, in patients who met response criteria during a 6-month induction trial. The… Expand
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Multicentric study comparing cyclosporine, mycophenolate mofetil and azathioprine in the maintenance therapy of lupus nephritis: 8 years follow up
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The Focal Segmental Glomerulosclerosis (FSGS) is one of the most frequent glomerular nephropathies affecting both children and adults. The aim of this study is the evaluation of the effects ofExpand
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TLDR
Long-term outcomes in terms of patient and renal survival of LN patients treated with CYP and MMF induction are similar, and most deaths occurred during induction, and sepsis was the most common cause of death. Expand
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