Mycophenolate mofetil is a highly effective and safe immunosuppressive agent for the treatment of uveitis

@article{Siepmann2005MycophenolateMI,
  title={Mycophenolate mofetil is a highly effective and safe immunosuppressive agent for the treatment of uveitis},
  author={K. Siepmann and M. Huber and N. St{\"u}biger and C. Deuter and M. Zierhut},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2005},
  volume={244},
  pages={788-794}
}
BackgroundWe evaluated the outcomes of patients with different forms of chronic uveitis treated with mycophenolate mofetil (MMF) as an immunomodulatory and steroid-sparing agent. The multi-system side effects that arise after long-term treatment with corticosteroids and other immunosuppressants prompted us to use MMF. MMF is a selective inhibitor of inosine monophosphate dehydrogenase, thus blocking purine synthesis via the de novo pathway preferentially used by T and B lymphocytes… Expand

Paper Mentions

Interventional Clinical Trial
In the First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Trial, the investigators propose to establish which immunosuppressive therapy, methotrexate or… Expand
ConditionsUveitis
InterventionDrug
Interventional Clinical Trial
The objective of this clinical trial is to evaluate the efficacy, safety and tolerability of enteric-coated mycophenolate sodium (Myfortic®) in combination with low-dose corticosteroids… Expand
ConditionsUveitis, Intermediate
InterventionDrug
Long-term results of therapy with mycophenolate mofetil in chronic non-infectious uveitis
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Efficacy and Safety of Mycophenolate Mofetil in the Treatment of Recalcitrant Intermediate Uveitis
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