Mycophenolate mofetil impairs healing of left-sided colon anastomoses.

  title={Mycophenolate mofetil impairs healing of left-sided colon anastomoses.},
  author={J{\"o}rg Zeeh and Roman Inglin and Gert Baumann and Olaf Dirsch and Nora E Riley and Guido G H Gerken and Markus W. B{\"u}chler and Bernhard Egger},
  volume={71 10},
INTRODUCTION Inadequate healing and consequent leakage from bowel anastomoses are a significant cause of postoperative morbidity and mortality. Immunosuppressive drugs are known to disturb healing processes and to impair the mechanical stability of bowel anastomosis. Mycophenolate mofetil (MMF) is an immunosuppressive agent that selectively inhibits the proliferation of T and B lymphocytes and has been shown to be effective in preventing allograft rejection after organ transplantation. Adverse… CONTINUE READING


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