Mycophenolate mofetil embryopathy may be dose and timing dependent.

  title={Mycophenolate mofetil embryopathy may be dose and timing dependent.},
  author={Ghee Soon Ang and Sheila A. Simpson and A. Ramaswamy Reddy},
  journal={American journal of medical genetics. Part A},
  volume={146A 15},
Mycophenolate mofetil (MMF) is an immunosuppressive agent that has now been recognized as teratogenic in humans. A pattern of malformations from in utero exposure to MMF has recently been described, and includes cleft lip and palate, microtia and atresia of the external auditory canal. We present a nulliparous mother who had taken MMF for recurrent erythema multiforme for the first 5 weeks of her pregnancy, and developed a spontaneous miscarriage during the seventh week of pregnancy. For her… CONTINUE READING