Mycophenolate mofetil/sirolimus compared to other common immunosuppressive regimens in kidney transplantation.

@article{Srinivas2007MycophenolateMC,
  title={Mycophenolate mofetil/sirolimus compared to other common immunosuppressive regimens in kidney transplantation.},
  author={Titte R. Srinivas and Jesse D. Schold and Giovanni Guerra and Aaron E. Eagan and Charles M Bucci and Herwig-Ulf Meier-Kriesche},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2007},
  volume={7 3},
  pages={
          586-94
        }
}
We evaluated outcomes with the sirolimus (SRL) and mycophenolate mofetil (MMF) combination regimen (SRL/MMF) in solitary kidney transplant recipients transplanted between 2000 and 2005 reported to the Scientific Registry of Renal Transplant Recipients. Three-and-a-half percent received SRL/MMF (n = 2040). Six-month acute rejection rates were higher with SRL/MMF (SRL/MMF: 16.0% vs. other regimens: 11.2%, p < 0.001). Overall graft survival was significantly lower on SRL/MMF. SRL/MMF was… CONTINUE READING

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