Mycophenolate Mofetil in Multiple Sclerosis

@article{Frohman2004MycophenolateMI,
  title={Mycophenolate Mofetil in Multiple Sclerosis},
  author={E. Frohman and K. Brannon and M. Racke and K. Hawker},
  journal={Clinical Neuropharmacology},
  year={2004},
  volume={27},
  pages={80-83}
}
Objective:To describe experience with the use of mycophenolate mofetil (MMF) in the treatment of multiple sclerosis (MS). Background:MMF is a potent immunosuppressant that is a selective inhibitor of inosine 5′-monophosphate dehydrogenase type II, the enzyme responsible for the de novo synthesis of the purine nucleotide guanine within activated T and B lymphocytes and macrophages. Methods:A retrospective review of experience in treating 79 MS patients with MMF (61 with secondary progressive, 14… Expand
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