Mycophenolate Mofetil as Second Line Therapy in Autoimmune Hepatitis?

  title={Mycophenolate Mofetil as Second Line Therapy in Autoimmune Hepatitis?},
  author={Elke M Hennes and Ye Htun Oo and Christoph Schramm and Ulrike W. Denzer and Peter Buggisch and Christiane Wiegard and Stephan Kanzler and Marcus Schuchmann and Wulf Otto Boecher and Peter R. Galle and David H Adams and Ansgar Wilhelm Lohse},
  journal={The American Journal of Gastroenterology},
INTRODUCTION:In patients with autoimmune hepatitis, efficient immunosuppressive therapy is essential to avoid progression to cirrhosis. There is no established second line therapy for patients failing standard therapy with steroids and azathioprine. The aim of this study was to examine the possible role of mycophenolate mofetil (MMF) as second line treatment of autoimmune hepatitis (AIH).PATIENTS AND ETHODS:We were able to identify 37 patients (29 women, 8 men) with AIH proven according to… CONTINUE READING