Mycoepoxydiene suppresses RANKL-induced osteoclast differentiation and reduces ovariectomy-induced bone loss in mice

Abstract

Mycoepoxydiene (MED) is a compound isolated from the marine fungal Diaporthe sp. HLY-1 associated with mangroves. MED has various biological effects such as anti-microbial, anti-cancer, and anti-inflammatory activities. However, the effect of MED on the differentiation of osteoclasts, the multinucleated bone-resorbing cells which play a crucial role in bone… (More)
DOI: 10.1007/s00253-012-4146-5

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Cite this paper

@article{Zhu2012MycoepoxydieneSR, title={Mycoepoxydiene suppresses RANKL-induced osteoclast differentiation and reduces ovariectomy-induced bone loss in mice}, author={Jingwei Zhu and Qiang Chen and Xiaochun Xia and Pingli Mo and Yuemao Shen and Chundong Yu}, journal={Applied Microbiology and Biotechnology}, year={2012}, volume={97}, pages={767-774} }