Mycobacterium vaccae induces a population of pulmonary CD11c+ cells with regulatory potential in allergic mice.

Abstract

The hygiene hypothesis proposes that common, harmless microorganisms, present throughout our evolutionary history, have helped to develop immunoregulatory mechanisms that prevent inappropriate immune responses by the host. Using a mouse model of allergic pulmonary inflammation, we report that treatment with an ubiquitous saprophytic mycobacterium… (More)
DOI: 10.1002/eji.200324659

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