Mycobacterium tuberculosis proteome microarray for global studies of protein function and immunogenicity.

@article{Deng2014MycobacteriumTP,
  title={Mycobacterium tuberculosis proteome microarray for global studies of protein function and immunogenicity.},
  author={J. Deng and L. Bi and Lin Zhou and Shu-juan Guo and J. Fleming and He-wei Jiang and Ying Zhou and Jia Gu and Qiu Zhong and Zong-xiu Wang and Z. Liu and Rui-ping Deng and Jing Gao and Tao Chen and Wenjuan Li and Jing-Fang Wang and Xu-de Wang and Hai-cheng Li and F. Ge and Guofeng Zhu and Hai-nan Zhang and J. Gu and Fan-lin Wu and Zhiping Zhang and Dianbin Wang and H. Hang and Y. Li and L. Cheng and Xiang He and S. Tao and Xian-En Zhang},
  journal={Cell reports},
  year={2014},
  volume={9 6},
  pages={
          2317-29
        }
}
Poor understanding of the basic biology of Mycobacterium tuberculosis (MTB), the etiological agent of tuberculosis, hampers development of much-needed drugs, vaccines, and diagnostic tests. Better experimental tools are needed to expedite investigations of this pathogen at the systems level. Here, we present a functional MTB proteome microarray covering most of the proteome and an ORFome library. We demonstrate the broad applicability of the microarray by investigating global protein-protein… Expand
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