Mycobacterium tuberculosis infection as a zoonotic disease: transmission between humans and elephants.

@article{Michalak1998MycobacteriumTI,
  title={Mycobacterium tuberculosis infection as a zoonotic disease: transmission between humans and elephants.},
  author={Krzysztof Michalak and Connie Austin and S. Diesel and Monica Bacon and Peter Zimmerman and Joel N. Maslow},
  journal={Emerging Infectious Diseases},
  year={1998},
  volume={4},
  pages={283 - 287}
}
Between 1994 and 1996, three elephants from an exotic animal farm in Illinois died of pulmonary disease due to Mycobacterium tuberculosis. In October 1996, a fourth living elephant was culture-positive for M. tuberculosis. Twenty-two handlers at the farm were screened for tuberculosis (TB); eleven had positive reactions to intradermal injection with purified protein derivative. One had smear-negative, culture-positive active TB. DNA fingerprint comparison by IS6110 and TBN12 typing showed that… CONTINUE READING