Mycobacterium tuberculosis Beijing genotype is an independent risk factor for tuberculosis treatment failure in Indonesia.

@article{Parwati2010MycobacteriumTB,
  title={Mycobacterium tuberculosis Beijing genotype is an independent risk factor for tuberculosis treatment failure in Indonesia.},
  author={Ida Parwati and Bachti Alisjahbana and Lika Apriani and Rista D Soetikno and Tom H. M. Ottenhoff and Adri G M van der Zanden and Jos W M van der Meer and Dick van Soolingen and Reinout van Crevel},
  journal={The Journal of infectious diseases},
  year={2010},
  volume={201 4},
  pages={553-7}
}
Animal studies have shown that the globally emerging Beijing genotype strains of Mycobacterium tuberculosis are more virulent than other strains. We examined whether Beijing strains increase treatment failure in a prospective cohort study in Indonesia. Among 818 tuberculosis cases, positive sputum culture results after 6 months of treatment were more common among patients infected with Beijing strains (33.4%) than among those infected with non-Beijing strains (relative risk, 1.94 [95… CONTINUE READING

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