Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation.

  title={Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation.},
  author={Audrey Bernut and Jean-Louis Herrmann and Karima Kissa and J F Dubremetz and J. -L. Gaillard and Georges Lutfalla and Laurent Kremer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={111 10},
Mycobacterium abscessus is a rapidly growing Mycobacterium causing a wide spectrum of clinical syndromes. It now is recognized as a pulmonary pathogen to which cystic fibrosis patients have a particular susceptibility. The M. abscessus rough (R) variant, devoid of cell-surface glycopeptidolipids (GPLs), causes more severe clinical disease than the smooth (S) variant, but the underlying mechanisms of R-variant virulence remain obscure. Exploiting the optical transparency of zebrafish embryos, we… CONTINUE READING