Mycobacteria: Bugs and bugbears (Two steps forward and one step back)

  title={Mycobacteria: Bugs and bugbears (Two steps forward and one step back)},
  author={T. Parish and N. Stoker},
  journal={Molecular Biotechnology},
  • T. Parish, N. Stoker
  • Published 1999
  • Medicine, Biology
  • Molecular Biotechnology
  • The use of molecular techniques to study the mycobacteria has advanced greatly since the first genomic libraries of Mycobacterium tuberculosis and M. leprae were constructed in 1985. However, there are still pitfalls for the unwary. Most of the problems associated with the use of molecular techniques to study mycobacteria can be related to one of the following problems: slow growth rate causing problems with contamination; the formation of macroscopic clumps when grown in culture; resistance to… CONTINUE READING
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