Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling

@article{Roussel1991MycRO,
  title={Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling},
  author={M. F. Roussel and J. Cleveland and S. Shurtleff and C. Sherr},
  journal={Nature},
  year={1991},
  volume={353},
  pages={361-363}
}
  • M. F. Roussel, J. Cleveland, +1 author C. Sherr
  • Published 1991
  • Biology, Medicine
  • Nature
  • THE colony-stimulating factor-1 receptor (CSF-1 R) mediates its pleiotropic effects through the coupling of its ligand-activated tyrosine kinase to multiple intracellular effector proteins, whose combined actions determine the magnitude and specificity of the biological response. The interaction of cytoplasmic signalling molecules with CSF-1 R is mediated in part by sequence motifs flanking sites of receptor tyrosine phosphorylation1. Mutation of an autophosphorylation site at tyrosine 809 in… CONTINUE READING
    154 Citations
    Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase.
    • 42
    • PDF
    Signal transduction by the macrophage-colony-stimulating factor receptor (CSF-1R)
    • M. Roussel
    • Biology, Medicine
    • Journal of Cell Science
    • 1994
    • 40
    • PDF
    Complementation of Defective Colony-Stimulating Factor 1 Receptor Signaling and Mitogenesis by Raf and v-Src
    • 58
    • PDF
    Scaffolding Protein Gab2 Mediates Differentiation Signaling Downstream of Fms Receptor Tyrosine Kinase
    • 101
    • PDF

    References

    SHOWING 1-10 OF 23 REFERENCES
    Mouse NIH 3T3 cells expressing human colony-stimulating factor 1 (CSF-1) receptors overgrow in serum-free medium containing human CSF-1 as their only growth factor.
    • M. Roussel, C. Sherr
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1989
    • 48
    • PDF