Myasthenia gravis

@article{Spillane2012MyastheniaG,
  title={Myasthenia gravis},
  author={Jennifer E. Spillane and Elizabeth Higham and Dimitri Michael Kullmann},
  journal={BMJ : British Medical Journal},
  year={2012},
  volume={345}
}
This is one of a series of occasional articles highlighting conditions that may be more common than many doctors realise or may be missed at first presentation. The series advisers are Anthony Harnden, university lecturer in general practice, Department of Primary Health Care, University of Oxford, and Richard Lehman, general practitioner, Banbury. To suggest a topic for this series, please email us at easilymissed@bmj.com. 

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Miyastenia gravis, iskelet kaslarında güçsüzlük ve çabuk yorulma ile karakterize bir kas hastalığıdır. Miyastenik hastalarda çeşitli nedenlerle miyastenik kriz gelişebilir. Bu olgu sunumunda solunumExpand
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References

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This review focuses on the diagnostic tests that may help to confirm myasthenia in patients without acetylcholine receptor antibodies, including the newly discovered anti-muscle-specific receptorExpand
Myasthenia gravis: a population based epidemiological study in Cambridgeshire, England
TLDR
This, the second highest reported prevalence for myasthenia, is likely to be the result of optimum case ascertainment, increased disease duration, application of complex diagnostic tests, and the impact of an aging population leading to a relative increase in the prevalence of ocular myastsia. Expand
Lifetime course of myasthenia gravis
TLDR
The clinical course of MG was significantly influenced by age and gender, and these need special attention in managing patients, and novel drugs need to be developed to increase the number as well as normal functioning of the AChRs and other components of the neuromuscular system. Expand
Myasthenia gravis: diagnosis and follow-up of 100 consecutive patients
Abstract One hundred consecutive patients with myasthenia gravis (MG) referred between 1985 and 1989 were analysed for epidemiological characteristics, evolution of early signs, delay in diagnosis,Expand
Myasthenia Gravis: A Review of Available Treatment Approaches
Patients with autoimmune myasthenia gravis (MG) should be further classified before initiating therapy, as treatment response varies for ocular versus generalised, early onset versus late onset, andExpand
The Epidemiology of Myasthenia Gravis
TLDR
The age and ethnic distributions in the United States are evolving from those that were present when the majority of population‐based studies were done, and the distribution of severity of the disease may also have changed, so future studies of the epidemiology of MG should take these factors into account. Expand
Myasthenia Gravis in the Elderly
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TLDR
It is shown that myasthenia gravis in the elderly is diagnosed more often today than previously, and the increase is mainly found in patients over the age of 50 years, which means Neurologists therefore see more old patients with MG now than before. Expand
Evidence of underdiagnosis of myasthenia gravis in older people
TLDR
The sharp fall in the incidence of clinically recognised myasthenia gravis in people over 80 years of age in the authors' national AChR antibody incidence study, and the high prevalence of previously unrecognised positive AchR antibodies in those ≥ 75 years old, suggest that myastshenia Gravis may be substantially underdiagnosed in older people. Expand
Myasthenia mimicking vertebrobasilar stroke
TLDR
This work presents two cases of myasthenia presenting as posterior circulation stroke, and in one case, the tempo suggested basilar thrombosis. Expand
Myasthenic crisis: Guidelines for prevention and treatment
TLDR
In the experience and based on a review of recent literature, the use of plasma exchange (PE) as a primary modality in the acute care setting, supported by other immunomodulatory medications such as corticosteroids is advocated. Expand
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