Myasthenia gravis: population differences in disease expression and acetylcholine receptor antibody titers between Chinese and Caucasians.

@article{Chiu1987MyastheniaGP,
  title={Myasthenia gravis: population differences in disease expression and acetylcholine receptor antibody titers between Chinese and Caucasians.},
  author={Hou Chang Chiu and Angela Vincent and John Newsom-Davis and K H Hsieh and T P Hung},
  journal={Neurology},
  year={1987},
  volume={37 12},
  pages={1854-7}
}
Clinical features and anti-acetylcholine receptor (AChR) titers were compared in Chinese (n = 258) and Caucasian (n = 258) myasthenia gravis populations. The former had more early onset and ocular cases, lacked the Caucasian late onset peak, and had fewer severe cases. The distribution of anti-AChR titers was broadly similar in the two populations, and their sera reacted equally well with AChR in both races. The significantly lower (chi 2 = 14.6; p less than 0.001) median anti-AChR titer in the… CONTINUE READING