Myasthenia gravis: a clinical-immunological update

@inproceedings{Binks2015MyastheniaGA,
  title={Myasthenia gravis: a clinical-immunological update},
  author={Sophie Binks and Angela C Vincent and Jackie Palace},
  booktitle={Journal of Neurology},
  year={2015}
}
Myasthenia gravis (MG) is the archetypic disorder of both the neuromuscular junction and autoantibody-mediated disease. In most patients, IgG1-dominant antibodies to acetylcholine receptors cause fatigable weakness of skeletal muscles. In the rest, a variable proportion possesses antibodies to muscle-specific tyrosine kinase while the remainder of seronegative MG is being explained through cell-based assays using a receptor-clustering technique and, to a lesser extent, proposed new antigenic… CONTINUE READING
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