Mutual occlusion of P2X ATP receptors and nicotinic receptors on sympathetic neurons of the guinea-pig.

@article{Searl1998MutualOO,
  title={Mutual occlusion of P2X ATP receptors and nicotinic receptors on sympathetic neurons of the guinea-pig.},
  author={Timothy J. Searl and Rachel S Redman and Eugene M. Silinsky},
  journal={The Journal of physiology},
  year={1998},
  volume={510 ( Pt 3)},
  pages={783-91}
}
1. The interaction of ion channels activated by nicotinic receptor agonists with ion channels gated by extracellular ATP (i.e. P2X receptors) was studied on sympathetic neurons acutely dissociated from coeliac ganglia of the guinea-pig. Patch clamp methods were used to measure the inward current generated through these non-selective cationic channels under voltage clamp. 2. At the whole cell level, the specific nicotinic receptor agonists nicotine (5-100 microM) or cytisine (50-75 microM) and… CONTINUE READING
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