Mutual interference of adenovirus infection and myc expression.

  title={Mutual interference of adenovirus infection and myc expression.},
  author={Kristina L{\"o}hr and Oliver Hartmann and Helmut Sch{\"a}fer and Matthias Dobbelstein},
  journal={Journal of virology},
  volume={77 14},
During infection with adenovirus, massive changes in the transcription of virus genes are observed, suggesting that the expression of cellular genes may also be modulated. To characterize the levels of cellular RNA species in infected cells, cDNA arrays were screened 24 h after infection of HeLa cells with wild-type adenovirus type 5, strain dl309. Despite complete transduction of the cells, fewer than 20 cellular genes (out of 4,600 analyzed and 1,200 found detectable and expressed above… CONTINUE READING
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