Mutual Interaction of Basophils and T Cells in Chronic Inflammatory Diseases

@inproceedings{Sarfati2015MutualIO,
  title={Mutual Interaction of Basophils and T Cells in Chronic Inflammatory Diseases},
  author={Marika Sarfati and Keiko Wakahara and Laurence Chapuy and Guy J. Delespesse},
  booktitle={Front. Immunol.},
  year={2015}
}
Basophils are, together with mast cells, typical innate effector cells of allergen-induced IgE-dependent allergic diseases. Both cell types express the high-affinity receptor for IgE (FcεR1), release histamine, inflammatory mediators, and cytokines following FcεR1 cross-linking. Basophils are rare granulocytes in blood, lymphoid, and non-lymphoid tissues, and the difficulties to detect and isolate these cells has hampered the study of their biology and the understanding of their possible role… CONTINUE READING
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