Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli

@article{Ebright1984MutationsTA,
  title={Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli},
  author={R. Ebright and P. Cossart and B. Gicquel-Sanzey and J. Beckwith},
  journal={Nature},
  year={1984},
  volume={311},
  pages={232-235}
}
Three mutations that alter the DNA sequence specificity of the catabolite gene activator protein (CAP) from AA-TGTGA--T---TCA-ATW to AA-TGTAA--T---TCA-ATW have been isolated. All three mutations affect the same amino acid of CAP, glutamic acid 181. We propose that it is this amino acid of CAP that makes contacts with base pairs 7 and 16 of the symmetrical recognition site. 
Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function.
  • N. Irwin, M. Ptashne
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1987
Activation of the lac Operon of Escherichia coli by a mutant FNR protein
Genetic identification of the DNA binding domain of Escherichia coli LexA protein.
  • A. Thliveris, D. Mount
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1992
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 40 REFERENCES
Cloning and sequence of the crp gene of Escherichia coli K 12.
A new class of promoter mutations in the lactose operon of Escherichia coli.
  • J. Hopkins
  • Biology, Medicine
  • Journal of molecular biology
  • 1974
Structural similarity in the DNA-binding domains of catabolite gene activator and cro repressor proteins.
...
1
2
3
4
...