Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer.

Abstract

BACKGROUND Inactivation of the p53 tumor suppressor gene (also known as TP53) through a point mutation and/or loss of heterozygosity is one of the most common genetic changes found in various types of human tumors. PURPOSE Our purpose was to investigate the relationship between the presence of p53 gene mutations and survival of patients with non-small… (More)

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Cite this paper

@article{Mitsudomi1993MutationsOT, title={Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer.}, author={Tetsuya Mitsudomi and Tokuhide Oyama and Tomokazu Kusano and Takako Osaki and Ryoichi Nakanishi and Takayuki Shirakusa}, journal={Journal of the National Cancer Institute}, year={1993}, volume={85 24}, pages={2018-23} }