Mutations of neuraminidase implicated in neuraminidase inhibitors resistance.

  title={Mutations of neuraminidase implicated in neuraminidase inhibitors resistance.},
  author={Olivier Ferraris and Bruno Lina},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  volume={41 1},
Influenza constitutes one of the most important upper respiratory tract infections regarding morbidity, and mortality. Prevention and treatment of influenza rely on inactivated vaccines and antiviral drugs. Zanamivir and Oseltamivir, the currently available influenza neuraminidase inhibitors (NAI) can be used in clinical practice for the treatment of influenza infection. These drugs have also shown their efficacy against highly pathogenic avian influenza. Recent transmission of avian H7N7 and… CONTINUE READING