Mutations of flagellar genes fliC12, fliA and flhDC of Edwardsiella tarda attenuated bacterial motility, biofilm formation and virulence to fish.

@article{Xu2014MutationsOF,
  title={Mutations of flagellar genes fliC12, fliA and flhDC of Edwardsiella tarda attenuated bacterial motility, biofilm formation and virulence to fish.},
  author={Tingting Xu and Ying Su and Y Xu and Yanan He and Bo Wang and Xiao Dong and Yitong Li and Xin-Hua Zhang},
  journal={Journal of applied microbiology},
  year={2014},
  volume={116 2},
  pages={236-44}
}
AIMS The aim of this study was to investigate functions of flagellar genes fliC2, fliC12, fliA and flhDC in a bacterial fish pathogen Edwardsiella tarda. METHODS AND RESULTS In this study, functions of flagellar genes, fliC2, fliC12 (fliC1 + fliC2), fliA and flhDC (flhD + flhC) of Edw. tarda H1 were analysed by constructing in-frame deletion mutants respectively and complementary strains fliC2(+) and fliA(+) . Electron microscopy revealed that in-frame deletion of fliC12, fliA and flhDC… CONTINUE READING

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