Mutations of DMYPT cause over constriction of contractile rings and ring canals during Drosophila germline cyst formation.


Ring canals, also known as stable intercellular bridges, are derived from the contractile rings of incomplete cytokinesis (IC) in most organisms. Formation of ring canals is necessary to generate functional eggs and sperm in multiple organisms including insects, birds, mammals and various plants. How the constriction of a contractile ring is arrested and… (More)
DOI: 10.1016/j.ydbio.2010.06.008


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