Mutations in the draT and draG genes of Rhodospirillum rubrum result in loss of regulation of nitrogenase by reversible ADP-ribosylation.

@article{Liang1991MutationsIT,
  title={Mutations in the draT and draG genes of Rhodospirillum rubrum result in loss of regulation of nitrogenase by reversible ADP-ribosylation.},
  author={Jon Liang and Gustav Nielsen and Douglas P Lies and Robert H. Burris and Gary P. Roberts and Paul W. Ludden},
  journal={Journal of bacteriology},
  year={1991},
  volume={173 21},
  pages={6903-9}
}
Reversible ADP-ribosylation of dinitrogenase reductase forms the basis of posttranslational regulation of nitrogenase activity in Rhodospirillum rubrum. This report describes the physiological effects of mutations in the genes encoding the enzymes that add and remove the ADP-ribosyl moiety. Mutants lacking a functional draT gene had no dinitrogenase reductase ADP-ribosyltransferase (DRAT, the draT gene product) activity in vitro and were incapable of modifying dinitrogenase reductase with ADP… CONTINUE READING