Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis


Congenital insensitivity to pain with anhidrosis (CIPA; MIM 256800) is an autosomal-recessive disorder characterized by recurrent episodes of unexplained fever, anhidrosis (absence of sweating) and absence of reaction to noxious stimuli, self-mutilating behaviour and mental retardation1–3. The genetic basis for CIPA is unknown. Nerve growth factor (NGF… (More)
DOI: 10.1038/ng0896-485


  • Presentations referencing similar topics